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pentobarbital will lower the extent or outcome of tramadol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Reduced AUC of tramadol as well as Lively metabolite (O-desmethyltramadol) when coadministered with potent CYP3A4 and CYP2B6 inducersIn Australia, Nembutal and secobarbital can be employed for animals, but are unla